Doyle D V, Dieppe P A, Scott J, Huskisson E C
Ann Rheum Dis. 1981 Feb;40(1):75-8. doi: 10.1136/ard.40.1.75.
An articular index was devised for the sequential assessment of patients with osteoarthritis (OA). Forty-eight joint units, chosen to reflect the characteristic pattern of the disease, were scored for tenderness on pressure or movement on a 4-point scale. Four observers examined patients to assess inter- and intraobserver error. The index was highly reproducible both within and between observers; intraobserver error was, however, significantly smaller. In a double-blind, cross-over trial the index was sufficiently sensitive to detect a statistically significant difference between the responses of patients with OA to an anti-inflammatory agent and to a simple analgesic. It is likely to be a useful addition to current methods of measurement in osteoarthritis.
设计了一个关节指数用于对骨关节炎（OA）患者进行连续评估。选择了48个关节单位以反映该疾病的特征模式，根据按压或活动时的压痛情况按4分制评分。四名观察者对患者进行检查以评估观察者间和观察者内误差。该指数在观察者之间和观察者内部都具有高度可重复性；然而，观察者内误差明显更小。在一项双盲交叉试验中，该指数足够敏感，能够检测出OA患者对抗炎药和简单镇痛药的反应之间具有统计学意义的差异。它很可能是骨关节炎现有测量方法的一个有用补充。
