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丝虫性乳糜尿相关性肾小球肾炎及乳糜尿患者的治疗考量

Filarial chyluria associated glomerulonephritis and therapeutic considerations in the chyluric patient.

作者信息

Waugh D A, Alexander J H, Ibels L S

出版信息

Aust N Z J Med. 1980 Oct;10(5):559-62. doi: 10.1111/j.1445-5994.1980.tb04977.x.

DOI:10.1111/j.1445-5994.1980.tb04977.x
PMID:7008760
Abstract

Two patients with chyluria who were successfully treated by surgical disconnection of the lymphatics from the renal pelvis are reported. One patient also had an associated glomerulonephritis, possibly secondary to filariasis. Although glomerulonephritis associated with filariasis has been reported previously the details of renal biopsies in man have included only light microscopic findings. In this patient immunofluorescent and electron microscopic studies showed mesangial deposits of immunoglobulins and complement which suggests that glomerulonephritis in patients with filariasis may be an immune complex type.

摘要

报告了两名乳糜尿患者,他们通过手术切断肾盂淋巴管而成功治愈。一名患者还伴有肾小球肾炎,可能继发于丝虫病。虽然此前已有丝虫病相关肾小球肾炎的报道,但人体肾活检的详细情况仅包括光镜检查结果。在该患者中,免疫荧光和电子显微镜研究显示系膜区有免疫球蛋白和补体沉积,这表明丝虫病患者的肾小球肾炎可能是免疫复合物型。

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Pathogenesis of lymphatic filariasis in man.人类淋巴丝虫病的发病机制。
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