Rosen M, Vaughan R S, Mapleson W W, Laurence K M, Hillard E K
Br J Anaesth. 1981 Mar;53(3):249-54. doi: 10.1093/bja/53.3.249.
In severe asphyxia, expansion of the newborn lung must precede ventilation by intermittent positive pressure. Inadequate expansion may lead to hypoxia and excessive expansion to rupture of the lung. The only way in which a predetermined pressure can be achieved, and not exceeded in the alveoli, is by applying that pressure at the mouth and waiting until all flow ceases. Applying pressure in this way and increasing it according to a "staircase" pattern, with appropriate steps at suitable intervals, should ensure that the maximum pressure produced in the alveoli is no greater than the minimum necessary for resuscitation in each individual infant. On the basis of published work, ranges of optimum values for the increments and time intervals are suggested. Clinical judgement is still necessary to select from within these ranges, but this "pressure staircase" method should provide a systematic approach to the problem. A suitable apparatus is described.
在重度窒息时,新生儿肺部扩张必须先于间歇正压通气。扩张不足可能导致缺氧,而过度扩张则可能导致肺破裂。在肺泡中实现预定压力且不超过该压力的唯一方法是在口腔施加该压力并等待直至所有气流停止。以这种方式施加压力并按照“阶梯式”模式增加压力,在适当的间隔设置适当的步长,应确保肺泡中产生的最大压力不大于每个婴儿复苏所需的最小压力。根据已发表的研究成果,提出了增量和时间间隔的最佳值范围。仍需要临床判断从这些范围内进行选择,但这种“压力阶梯”方法应为解决该问题提供一种系统的方法。文中描述了一种合适的设备。