Wolfson N, Riley J, Samuels B, Singh J M
Clin Toxicol. 1981 Jan;18(1):41-5. doi: 10.3109/15563658108990012.
Clotrimazole, a tritylimidazole and a new antimicrobial agent, produced itching and irritation of the vulva and vaginal area in less than 1% of the population (N = 131) studied. No abdominal cramps, headache or lightheadedness, nausea, vomiting, and diarrhea were observed when 200 mg of clotrimazole was inserted deep in the vagina for several days.
克霉唑,一种三苯甲基咪唑类新型抗菌剂,在研究的不到1%的人群(N = 131)中会引起外阴和阴道区域的瘙痒与刺激。当200毫克克霉唑被深部插入阴道数天时,未观察到腹部绞痛、头痛或头晕、恶心、呕吐及腹泻等症状。