碱性磷酸酶调节突变phoB和phoT对大肠杆菌厌氧生长及多聚磷酸盐合成的多效性影响
Pleiotropic effects of alkaline phosphatase regulatory mutations phoB and phoT on anaerobic growth of and polyphosphate synthesis in Escherichia coli.
作者信息
Zuckier G, Ingenito E, Torriani A
出版信息
J Bacteriol. 1980 Aug;143(2):934-41. doi: 10.1128/jb.143.2.934-941.1980.
Abstract
The appearance during anaerobiosis of spontaneous phoT phoB double mutants in a phoT background is described. During both exponential growth and stationary phase, selection against the phoT mutants relative to the wild type was evident. This reduction in viability of phoT mutants was suppressed in phoT phoB double mutants. Sensitivity to anaerobiosis was shown to be correlated with polyphosphate overproduction. A possible pleiotropic function of phoT and phoB is suggested.
摘要
描述了在厌氧条件下，以phoT为背景的自发phoT phoB双突变体的出现情况。在指数生长期和稳定期，相对于野生型，对phoT突变体的选择作用都很明显。phoT phoB双突变体中phoT突变体这种活力的降低得到了抑制。结果表明，对厌氧的敏感性与多聚磷酸盐的过量产生有关。文中提出了phoT和phoB可能的多效性功能。
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本文引用的文献
1
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J Bacteriol. 1965 May;89(5):1262-70. doi: 10.1128/jb.89.5.1262-1270.1965.
2
ISOLATION OF A PROTEIN SPECIFIED BY A REGULATOR GENE.调节基因所指定蛋白质的分离
J Mol Biol. 1964 Jun;8:841-52. doi: 10.1016/s0022-2836(64)80165-0.
3
ACCUMULATION OF INORGANIC POLYPHOSPHATE IN AEROBACTER AEROGENES. II. ENVIRONMENTAL CONTROL AND THE ROLE OF SULFUR COMPOUNDS.产气气杆菌中无机多磷酸盐的积累。II. 环境控制及硫化合物的作用。
J Bacteriol. 1963 Aug;86(2):222-31. doi: 10.1128/jb.86.2.222-231.1963.
4
ACCUMULATION OF INORGANIC POLYPHOSPHATE IN AEROBACTER AEROGENES. I. RELATIONSHIP TO GROWTH AND NUCLEIC ACID SYNTHESIS.产气气杆菌中无机多聚磷酸盐的积累。I. 与生长和核酸合成的关系。
J Bacteriol. 1963 Aug;86(2):216-21. doi: 10.1128/jb.86.2.216-221.1963.
5
Mutants of Aerobacter aerogenes blocked in the accumulation of inorganic polyphosphate.
J Gen Microbiol. 1963 May;31:241-6. doi: 10.1099/00221287-31-2-241.
6
Genetic control of repression of alkaline phosphatase in E. coli.大肠杆菌中碱性磷酸酶阻遏的遗传控制
J Mol Biol. 1961 Aug;3:425-38. doi: 10.1016/s0022-2836(61)80055-7.
7
The determination of phosphorus and phosphatase with N-phenyl-p-phenylenediamine.用N-苯基对苯二胺测定磷和磷酸酶
J Biol Chem. 1957 Mar;225(1):177-83.
8
Inorganic polyphosphates in biology: structure, metabolism, and function.生物学中的无机多聚磷酸盐：结构、代谢与功能
Bacteriol Rev. 1966 Dec;30(4):772-94. doi: 10.1128/br.30.4.772-794.1966.
9
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