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[健康、新生及癌性兔血清蛋白对心肌线粒体摄氧的影响]

[Effect of blood serum proteins of healthy, newborn and carcinomatous rabbits on oxygen uptake by myocardium mitochondria].

作者信息

Fedorova G P, Bila V M, Korotkoruchko V P

出版信息

Ukr Biokhim Zh. 1977 May-Jun;49(3):114-20.

PMID:70097
Abstract

Oxygen uptake by myocardium mitochondria in healthy rabbits and those suffering from cancer was studied as affected by blood sera and beta-globulin of newborn rabbits, pregnant female rabbits, healthy and carcinomatous rabbits. Respiration of myocardium mitochondria in healthy rabbits is inhibited under the effect of sera and beta-globulin of newborn rabbits and pregnant female rabbits. But the mentioned additives produce an opposite effect on oxygen uptake by myocardium mitochondria in the rabbit suffering from cancer as compared to myocardium mitochondria in the healthy rabbit. The difference in the protein action on oxygen uptake is levelled in the animals of different groups for mitochondria destructed under the effect of temperature and supersound.

摘要

研究了新生兔、妊娠母兔、健康兔和患癌兔的血清及β-球蛋白对健康兔和患癌兔心肌线粒体摄氧的影响。新生兔和妊娠母兔的血清及β-球蛋白会抑制健康兔心肌线粒体的呼吸。但与健康兔的心肌线粒体相比,上述添加剂对患癌兔的心肌线粒体摄氧产生相反的影响。在温度和超声作用下被破坏的线粒体中,不同组动物蛋白质对摄氧作用的差异趋于平衡。

相似文献

1
[Effect of blood serum proteins of healthy, newborn and carcinomatous rabbits on oxygen uptake by myocardium mitochondria].[健康、新生及癌性兔血清蛋白对心肌线粒体摄氧的影响]
Ukr Biokhim Zh. 1977 May-Jun;49(3):114-20.
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[Effect of various respiration substrates and growth marker proteins on oxygen consumption in rabbit heart mitochondria].[不同呼吸底物和生长标记蛋白对兔心脏线粒体氧消耗的影响]
Ukr Biokhim Zh (1978). 1983 Jan-Feb;55(1):64-8.
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Absence of the relationship between ultrastructure and metabolic state of heart mitochondria in situ.心脏线粒体原位超微结构与代谢状态之间关系的缺失。
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