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[正常生长典型的血液蛋白激活糖酵解并抑制巴斯德效应的能力]

[Ability of blood protein, typical of normal growth, to activate glycolysis and inhibit the Pasteur reaction].

作者信息

Bila V N, Korotkoruchko V P

出版信息

Ukr Biokhim Zh. 1977 Mar-Apr;49(2):78-82.

PMID:68614
Abstract

Formation of lactic acid by the extracts from the healthy rabbit muscles was studied as affected by the sera of embryos, newborn rabbits and pregnant female rabbits. The blood sera and beta-globulin isolated from them are established to activate anaerobic glycolysis and inhibit the Pasteur reaction. It is shown that protein typical of normal growth, belonging to beta-globulins and circulating in blood of the embryos, newborn rabbits from the first to the fifteenth day of development is "responsible" for this phenomena. Correlation is found between the precipitation test for detecting this protein and its biological effect on glycolysis and the Pasteur reaction.

摘要

研究了胚胎、新生兔和怀孕母兔的血清对健康兔肌肉提取物产生乳酸的影响。已证实从它们中分离出的血清和β-球蛋白可激活无氧糖酵解并抑制巴斯德效应。结果表明,胚胎、发育第1天至第15天的新生兔血液中循环的、属于β-球蛋白的典型正常生长蛋白是造成这种现象的“原因”。发现检测该蛋白的沉淀试验与其对糖酵解和巴斯德效应的生物学效应之间存在相关性。

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Ukr Biokhim Zh. 1977 Mar-Apr;49(2):78-82.
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