Avtandilov G G, Kozlovskiĭ O M, Kosenkova S T, Peshkova I A
Vopr Onkol. 1981;27(2):20-6.
To elaborate certain objective rules for the differential cytological classification of gastric cancer the initial material was studied, which was obtained from 100 gastric cancer patients based on cytological characteristics for 28 morphometric parameters. The results were processed on a computer by an approximation method of statistical classification, and 4 taxons were obtained: the 1st taxon (21 observations) comprised "diffuse" type tumors, characterized cytologically by an isolated arrangement of mucous and signet-ring cells; the 2d and 3d taxons (10 and 51 observations combined "intestinal" type gastric cancer, characterized by adenous complexing of columnar cells without mucus in the cytoplasm; the 4th taxon is characterized by the greatest variance in morphometrical indices and included tumors of anaplastic gastric cancer. The cytostatistical classification according to cell types corresponds to the Lauren histological classification of gastric cancer.