Zeissler R, Wenzel U D, Strauch W
Arch Exp Veterinarmed. 1980;34(6):861-76.
Twelve different enzyme activities, which are listed and explained in greater detail in Table 2, were determined statistically secured, and discussed, following a three-year study into arterial plasma of 118 female and 124 male minks, aged between six and seven months and kept under anaesthesia. Simply normally distributed or logarithmically distributed plasma enzyme activities were found to differ primarily by sex, with other experimental conditions being identical and regular. The enzyme activities of ICDH, active CPK, and total LDH (the latter only with females) were normally distributed, whereas all the other enzymes activities tested, except for gamma-GT and SDH, were of Gaussian distribution only after logarithmic transformation of the individual values. The plasma enzyme activities of GPT, LAP, ChE, LDH1, MDH, and AP differed from those of GOT, gamma-GT, SDH, total LDH and active CPK, in that they usually exhibited highly significant sex-related differences. All minks were tranquilised and kept under general anaesthesia, using neuroleptanalgesia, but all their enzyme activities were found to vary just as widely as those reported elsewhere in literature, in the context of minks without anaesthesia. The latter result was experimentally confirmed by means of a model experiment in which enzyme activities were recorded from nine male ferrets, prior to, during, and after neuroleptanalgesia.
在对118只雌性和124只雄性水貂的动脉血浆进行了为期三年的研究后，测定、统计分析并讨论了12种不同的酶活性，表2中对这些酶活性有更详细的列举和解释。这些水貂年龄在6至7个月之间，处于麻醉状态。在其他实验条件相同且规律的情况下，发现简单呈正态分布或对数分布的血浆酶活性主要因性别而异。异柠檬酸脱氢酶（ICDH）、活性肌酸磷酸激酶（CPK）和总乳酸脱氢酶（仅雌性水貂的总乳酸脱氢酶）的酶活性呈正态分布，而除γ-谷氨酰转移酶（gamma-GT）和山梨醇脱氢酶（SDH）外，所有其他测试的酶活性在对个体值进行对数转换后才呈高斯分布。谷丙转氨酶（GPT）、亮氨酸氨基肽酶（LAP）、胆碱酯酶（ChE）、乳酸脱氢酶1（LDH1）、苹果酸脱氢酶（MDH）和碱性磷酸酶（AP）的血浆酶活性与谷草转氨酶（GOT）、γ-谷氨酰转移酶、山梨醇脱氢酶、总乳酸脱氢酶和活性肌酸磷酸激酶的血浆酶活性不同，因为它们通常表现出高度显著的性别相关差异。所有水貂都使用神经安定镇痛法进行了镇静并处于全身麻醉状态，但发现它们所有的酶活性变化范围与文献中报道的未麻醉水貂的酶活性变化范围一样大。通过一项模型实验对后一结果进行了实验验证，该实验记录了9只雄性雪貂在神经安定镇痛前、期间和之后的酶活性。
