Hoffer K J, Phillippi G
J Am Intraocul Implant Soc. 1978 Jan;4(1):18-23. doi: 10.1016/s0146-2776(78)80007-x.
Endothelial cell counts were taken of the superior, central and inferior corneas of controls, immediate post-operative cases and a four year post-operative case. A vertical mean cell density was found to correlate well with central densities, and mean vertical cell loss (42%) compared well with central cell loss (44%). There was no trend for vertical cell disparity (VCD) in control eye, but a definite disparity was seen in all post-operative eyes, including the one four years after surgery. A cell membrane stimulus theory is proposed for endothelial cell reparation after endothelial damage describing cessation of cell migration once the defect is covered.
对对照组、术后即刻病例以及术后四年病例的角膜上、中、下部分进行内皮细胞计数。发现垂直平均细胞密度与中央密度具有良好的相关性，平均垂直细胞丢失率（42%）与中央细胞丢失率（44%）相当。在对照眼中，垂直细胞差异（VCD）没有趋势，但在所有术后眼中，包括术后四年的那只眼睛，都出现了明显的差异。提出了一种细胞膜刺激理论，用于描述内皮损伤后内皮细胞修复的过程，即一旦缺损被覆盖，细胞迁移就会停止。
