Rackley C E, Russell R O, Rogers W J, Mantle J A, McDaniel H G, Reddy W J
Cardiovasc Clin. 1981;11(3):163-77.
The clinical understanding of determinants of mechanical function and oxygen requirements of the myocardium have now been applied to the patient with acute myocardial infarction. Invasive and noninvasive techniques to quantitate afterload, contractile state, preload, and heart rate as well as to assess the metabolic state and infarct size are now available to evaluate a growing list of therapeutic interventions. Thus, the availability of pharmacologic and metabolic agents to support ischemic myocardium and to reduce the eventual loss of contracting myocardium appears promising to the patient with acute myocardial infarction.
目前，对心肌机械功能和氧需求决定因素的临床认识已应用于急性心肌梗死患者。现在已有有创和无创技术来定量后负荷、收缩状态、前负荷和心率，以及评估代谢状态和梗死面积，以评估越来越多的治疗干预措施。因此，对于急性心肌梗死患者来说，使用药物和代谢药物来支持缺血心肌并减少最终收缩心肌的损失似乎前景乐观。
