Rackley C E, Satler L F, Pearle D L, Del Negro A A, Pallas R S, Kent K M
Cardiovasc Clin. 1986;16(3):3-15.
The modern coronary care unit now can provide hemodynamic measurements that characterize the determinants of myocardial oxygen consumption and mechanical performance. These determinants of preload, afterload, contractile state, and heart rate can be obtained from measurements with the Swan-Ganz catheter, systemic blood pressure, assessment of ventricular function, and heart rate. With the hemodynamic characterization of the determinants of left ventricular function, drugs can be selected that either decrease or increase the specific determinants in order to optimize left ventricular performance. Thus, a physiologic approach can be taken to the pharmacologic management of patients with acute myocardial infarction based on hemodynamic measurements and appropriate therapeutic strategies.
现代冠心病监护病房现在能够提供血流动力学测量，这些测量可表征心肌耗氧量和机械性能的决定因素。前负荷、后负荷、收缩状态和心率的这些决定因素可通过使用 Swan-Ganz 导管进行测量、测量体循环血压、评估心室功能以及测量心率来获得。通过对左心室功能决定因素进行血流动力学表征，可以选择能够降低或增加特定决定因素的药物，以优化左心室性能。因此，基于血流动力学测量和适当的治疗策略，可以采取生理学方法对急性心肌梗死患者进行药物治疗。
