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神经鞘瘤的超微结构,重点关注Antoni B组织。

The ultrastructure of neurilemoma with emphasis on Antoni B tissue.

作者信息

Sian C S, Ryan S F

出版信息

Hum Pathol. 1981 Feb;12(2):145-60. doi: 10.1016/s0046-8177(81)80102-5.

DOI:10.1016/s0046-8177(81)80102-5
PMID:7011937
Abstract

Ten neurilemomas were studied by electron microscopy. Antoni A and B tissues were identified by light microscopy on semithin sections, and the corresponding areas on adjacent ultrathin sections were studied ultrastructurally. The Antoni B tissue definitely possessed features of degeneration in that the cells showed a detached basal lamina, a disrupted cell membrane, degenerated nuclei, and a significant accumulation of cytoplasmic granules and myelin figures. Added to these was intercellular edema with fibrin. The similarity of the granules in the cells of Antoni B tissue, cells of granular cell tumor, and Schwann cells in wallerian degeneration supports the conclusion that these three are related phenomena.

摘要

对10例神经鞘瘤进行了电子显微镜研究。通过半薄切片的光学显微镜鉴定了Antoni A和B组织,并对相邻超薄切片上的相应区域进行了超微结构研究。Antoni B组织肯定具有退化特征,即细胞显示出脱离的基膜、破裂的细胞膜、退化的细胞核以及细胞质颗粒和髓鞘样结构的显著积累。除此之外还有伴有纤维蛋白的细胞间水肿。Antoni B组织的细胞、颗粒细胞瘤的细胞和华勒氏变性中的施万细胞内颗粒的相似性支持了这三种现象相关的结论。

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