Lamberton R P, Noth R H, Glickman M
J Urol. 1981 Apr;125(4):477-80. doi: 10.1016/s0022-5347(17)55077-6.
A retrospective analysis of 12 hypertensive patients with unilateral renal parenchymal disease was done to evaluate the roles of renal vein renin testing and an operation. The patients were considered to have renal parenchymal disease on the basis of radiographic and/or pathologic findings. Only 2 patients had positive renal vein renin studies. Both of these patients were improved after unilateral nephrectomy but 1 had subsequent progression of disease and renal failure. Of the 10 patients with negative studies 5 had unilateral nephrectomy: 4 of them, nevertheless, experienced substantial improvement in the hypertension. It is concluded that hypertensive patients with unilateral renal parenchymal disease often can benefit from an operation and that renal vein renin testing in such patients can be misleading.
对12例单侧肾实质疾病高血压患者进行回顾性分析，以评估肾静脉肾素检测及手术的作用。根据影像学和/或病理检查结果，这些患者被认为患有肾实质疾病。仅2例患者肾静脉肾素检查呈阳性。这2例患者在接受单侧肾切除术后病情均有改善，但其中1例随后疾病进展并出现肾衰竭。10例检查结果为阴性的患者中有5例接受了单侧肾切除术：然而，其中4例患者的高血压病情有显著改善。得出的结论是，单侧肾实质疾病高血压患者通常可从手术中获益，而此类患者的肾静脉肾素检测可能会产生误导。
