Torkelson S J, Gibson Q H
J Biol Chem. 1978 Oct 25;253(20):7331-5.
Determinations of carbon monoxide binding curves for hemoglobin from Brevoortia tyrannus under equilibrium and photostationary conditions show that in the light, the curve is shifted to the right and altered in shape. The Bohr effect is much less in the light. The kinetics of the transition between equilibrium and photostationary states has been examined. All of the results are satisfactorily described using the two-state model of Monod, J. Wyman, J., and Changeux, J.P. (1965) J. Mol. Biol. 12, 88-118 with the assumption that light produces an additive increase in the rate of dissociation of ligand from the R and T states.
对布氏鲱血红蛋白在平衡态和光稳态条件下的一氧化碳结合曲线的测定表明，在光照下，曲线向右移动且形状改变。光照下的玻尔效应要小得多。已经研究了平衡态和光稳态之间转变的动力学。假设光使配体从R态和T态解离的速率呈加性增加，使用莫诺德、怀曼和尚热（1965年，《分子生物学杂志》第12卷，88 - 118页）的两态模型可以令人满意地描述所有结果。
