酶固定于肝素上。
Enzyme immobilization on heparin.
作者信息
Torchilin V P, Il'ina E V, Streltosova Z A, Smirnov V N, Chazov E I
出版信息
J Biomed Mater Res. 1978 Sep;12(5):585-90. doi: 10.1002/jbm.820120502.
PMID:701296
Abstract
We describe the preparation and some of the properties of heparin-bound alpha-chymotrypsin that were obtained via activation of heparin with water-soluble carbodiimide. Immobilized enzyme has unchanged kinetic characteristics toward low-molecular- weight and macromolecular substrates. The heparin-bound enzymes could have a wide range of medical applications.
摘要
我们描述了通过水溶性碳二亚胺活化肝素所制备的肝素结合α-糜蛋白酶及其一些特性。固定化酶对低分子量和大分子底物具有不变的动力学特征。肝素结合酶可能有广泛的医学应用。
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