A method for multiple intraarterial injections in the allogeneic or isogeneic transplanted rat kidney by use of a long term catheter in the renal artery.

An experimental model using a permanent catheter in the artery of a transplanted rat kidney is presented. The experimental set-up allows selective infusion or injection into the renal circulation of unrestrained non anesthetized rats. It is also possible to make repeated studies of the renal circulation in a rejecting rat kidney transplant. Preliminary investigations and future applications are discussed.