Tight R R, Leland D, French M L
Sex Transm Dis. 1981 Jan-Mar;8(1):8-11. doi: 10.1097/00007435-198101000-00003.
Sera from 167 apparently normal rabbits were screened by the Venereal Disease Research Laboratory (VDRL) slide test and by the fluorescent treponemal antibody-absorption (FTA-Abs) and microhemagglutination assay for Treponema pallidum antibodies (MHA-TP) test. Three sera (1.8%) were reactive in all three tests, a fact suggesting possible inapparent infection with Treponema paraluis-cuniculi. One hundred forty-four sera (86.2%) were nonreactive in all tests. The VDRL slide test was reactive with 22 sera (13.2%). In 19 of these, treponemal tests were nonreactive; thus the rabbits probably were not infected with pathogenic treponemes. One hundred sixty-three sera (97.6%) were nonreactive in both treponemal tests, and three sera (1.8%) were reactive in both. One serum was reactive in the FTA-Abs test and nonreactive in the MHA-TP test. The lower incidence of reactivity with treponemal tests suggests that the FTA-Abs and MHA-TP tests are more useful than the VDRL slide test for screening rabbits intended for experimental studies of syphilis.
采用性病研究实验室（VDRL）玻片试验、梅毒螺旋体荧光抗体吸收试验（FTA-Abs）和梅毒螺旋体微量血凝试验（MHA-TP），对167只外观正常的家兔血清进行检测。3份血清（1.8%）在所有三项检测中均呈阳性反应，这一结果提示可能存在兔梅毒螺旋体隐性感染。144份血清（86.2%）在所有检测中均呈阴性反应。VDRL玻片试验有22份血清（13.2%）呈阳性反应。其中19份血清的梅毒螺旋体检测呈阴性反应，因此这些家兔可能未感染致病性梅毒螺旋体。163份血清（97.6%）在两项梅毒螺旋体检测中均呈阴性反应，3份血清（1.8%）在两项检测中均呈阳性反应。1份血清在FTA-Abs试验中呈阳性反应，而在MHA-TP试验中呈阴性反应。梅毒螺旋体检测阳性反应发生率较低，这表明FTA-Abs和MHA-TP试验在筛选用于梅毒实验研究的家兔时，比VDRL玻片试验更有用。
