Mottironi V D, Perryman L E, Pollara B, Mickey M R, Swift R, McGrath P
Transplantation. 1981 Apr;31(4):290-4. doi: 10.1097/00007890-198104000-00011.
Combined immunodeficiency disease (CID) is a genetic disorder of T and B lymphocyte production which results in a nonfunctional immune system. It is inherited as an autosomal recessive trait and has been reported in humans and in horses of the Arabian breed. Arabian horses known to have the CID gene and horses of unknown carrier status were tested using a microlymphocytotoxicity technique. Computer chi 2 analysis distinguished six serologically defined specificities. The study of unrelated horses and a limited number of families showed that the specificities behave as codominant alleles segregating at one locus. No differences in antigen frequency was detected between the CID carriers and the random horse population.
联合免疫缺陷病（CID）是一种T和B淋巴细胞生成的遗传性疾病，会导致免疫系统功能失调。它以常染色体隐性性状遗传，在人类和阿拉伯品种的马匹中都有报道。使用微量淋巴细胞毒性技术对已知携带CID基因的阿拉伯马和未知携带状态的马匹进行了检测。计算机卡方分析区分出六种血清学定义的特异性。对无关马匹和有限数量家族的研究表明，这些特异性表现为在一个基因座上分离的共显性等位基因。在CID携带者和随机马匹群体之间未检测到抗原频率的差异。
