Rosenkilde C E, Rosvold H E, Mishkin M
Brain Res. 1981 Apr 6;210(1-2):129-44. doi: 10.1016/0006-8993(81)90890-8.
Monkeys with ablations of the cortex in the principal sulcus who were impaired on a spatial delayed reaction test were unimpaired on a time discrimination test in which length of time since the last trial signalled the spatial position of the correct foodwell. The finding undermines the view that the classical delayed reaction deficit after lateral prefrontal lesions reflects the loss of temporal structuring of the stream of sensory input. The result is consistent instead with the alternative view that the classical deficit reflects a spatial memory disorder. Monkeys with inferior prefrontal ablations were impaired on both spatial tasks, and on object discrimination reversal as well; analysis of their deficits indicated that they were instances of perseverative interference. Finally, monkeys with ablations of the cortex in the arcuate sulcus were not consistently impaired on any of the tasks. There is no evidence from these results that prefrontal cortex plays any role in time perception.
在空间延迟反应测试中受损的、其主要沟回皮质被切除的猴子，在时间辨别测试中并未受损，在该测试中，自上次试验以来的时间长度表明了正确食槽的空间位置。这一发现削弱了以下观点，即外侧前额叶损伤后典型的延迟反应缺陷反映了感觉输入流的时间结构丧失。相反，该结果与另一种观点一致，即典型缺陷反映了空间记忆障碍。前额叶下部被切除的猴子在两项空间任务以及物体辨别反转任务中均受损；对它们缺陷的分析表明，这些都是持续性干扰的实例。最后，弓形沟回皮质被切除的猴子在任何任务中都没有持续受损。这些结果没有证据表明前额叶皮质在时间感知中起任何作用。
