Wright D H, Isaacson P
Cancer. 1981 Mar 1;47(5):915-25. doi: 10.1002/1097-0142(19810301)47:5<915::aid-cncr2820470517>3.0.co;2-v.
Three children with follicular center cell lymphomas are reported. The tumors were studied by light microscopy, electron microscopy, and the immunoperoxidase technique. All three tumors contained monotypic immunoglobulin; one had the morphology of a 'signet ring cell lymphoma,' and one had arisen in a child with Bloom's syndrome. Two tumors exhibited a nodular or partly nodular growth pattern. The tumors were compared with African cases of Burkitt's lymphoma and found to have marked differences in their morphologic and immunohistochemical characteristics. The authors believe that one should distinguish between Burkitt's lymphoma and follicular center cell lymphomas occurring in childhood.
本文报告了3例滤泡中心细胞淋巴瘤患儿。通过光学显微镜、电子显微镜和免疫过氧化物酶技术对肿瘤进行了研究。所有3例肿瘤均含有单型免疫球蛋白；1例具有“印戒细胞淋巴瘤”的形态，1例发生于患有布卢姆综合征的儿童。2例肿瘤表现为结节状或部分结节状生长模式。将这些肿瘤与非洲的伯基特淋巴瘤病例进行比较，发现它们在形态学和免疫组织化学特征上有明显差异。作者认为，应区分儿童期发生的伯基特淋巴瘤和滤泡中心细胞淋巴瘤。
