Singh D S, Bala-Subramaniam R, Bhatia V N, Kumar V, Chandrasekar S
Chemotherapy. 1981;27(3):220-3. doi: 10.1159/000237981.
50 cases with hookworm infestation were studied to find out the species of the parasite, 25 of them were included for a double-blind trial of compound Go.9333 (Ciba-Geigy)/placebo. Results of the study revealed predominance of Necator americanus (96%) in and around Pondicherry, South India. Compound Go.9333 was found to very effective in the treatment of hookworm infestation. Side effects were minor and were not of much significance. The drug was well accepted and tolerated by most of the cases. On the basis of the present study, compound Go.9333 can be recommended for the treatment of hookworm infestation.
对50例钩虫感染病例进行了研究，以确定寄生虫的种类，其中25例被纳入复方Go.9333（汽巴-嘉基公司生产）/安慰剂双盲试验。研究结果显示，在印度南部本地治里及其周边地区，美洲板口线虫占主导地位（96%）。发现复方Go.9333对治疗钩虫感染非常有效。副作用较小，没有太大影响。大多数病例对该药物接受良好且耐受性良好。基于本研究，复方Go.9333可推荐用于治疗钩虫感染。
