Pflücke F
Dtsch Z Verdau Stoffwechselkr. 1981;41(1):13-7.
Postcibal provoked gastrooesophageal reflux of 14 patients with symptoms of reflux was reduced significantly by metoclopramide (Cerucal, 10 mg i. v. or p. o.) for a period of at least 4 hours. Especially metoclopramide was effective in patients with severe symptoms and on 2 patients with endoscopically evident oesophagitis. Metoclopramide was ineffective in 4 patients with slight symptoms whereby therapeutic ineffectiveness may result.
对于14例有反流症状的患者,甲氧氯普胺(胃复安,静脉注射或口服10毫克)可使餐后诱发的胃食管反流在至少4小时内显著减轻。尤其是甲氧氯普胺对症状严重的患者以及2例有内镜可见食管炎的患者有效。甲氧氯普胺对4例症状轻微的患者无效,这可能导致治疗无效。