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[实验大鼠的昼夜节律(一般特征及内分泌方面)]

[Circadian rhythms in laboratory rats (general characteristics and endocrine aspects)].

作者信息

Stoĭnev A, Ikonomov O

出版信息

Eksp Med Morfol. 1981;20(1):1-7.

PMID:7014190
Abstract

The authors present data on the circadian fluctuations of some important functional and biochemical indices in laboratory rats: motor activity, sleep, body temperature, intake of food and water, renal excretion, plasma proteins, glucose, electrolytes, non-organic phosphates and osmolality, hematocrit, corticotropin-releasing hormone (C-RH), adenocorticotropic hormone (ACTH), plasma and adrenal corticosterone, plasma renin activity (PRA), aplasma aldosterone, insulin and antidiuretic hormone (ADH). They describe the participation of the central nervous system in the regulation of circadian rhythms of rats as they present the newest data on the participation of suprachiasmatic hypothalamic nucleus and the sympathicus part of the vegetative nervous system. The significance of knowledge of circadian rhythms for correct interpretation of the obtained experimental data is explained. A mode of work by placing the rats at reverse regimen of lighting is presented. This gives a possibility that the results, obtained from the at night active types of rats, could be compared with those, obtained from the daily active laboratory animals and persons.

摘要

作者展示了实验室大鼠一些重要功能和生化指标的昼夜波动数据

运动活动、睡眠、体温、食物和水的摄入量、肾脏排泄、血浆蛋白、葡萄糖、电解质、无机磷酸盐和渗透压、血细胞比容、促肾上腺皮质激素释放激素(C-RH)、促肾上腺皮质激素(ACTH)、血浆和肾上腺皮质酮、血浆肾素活性(PRA)、血浆醛固酮、胰岛素和抗利尿激素(ADH)。他们描述了中枢神经系统在大鼠昼夜节律调节中的参与情况,同时展示了关于下丘脑视交叉上核和自主神经系统交感部分参与的最新数据。解释了了解昼夜节律对于正确解读所获实验数据的重要性。介绍了通过将大鼠置于反向光照方案下的工作模式。这使得从夜间活动型大鼠获得的结果能够与从白天活动的实验动物和人类获得的结果进行比较。

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