癌胚抗原存在于人体外分泌汗液中。

Carcinoembryonic antigen present in human eccrine sweat.

作者信息

Penneys N S, Nadji M, McKinney E C

出版信息

J Am Acad Dermatol. 1981 Apr;4(4):401-3. doi: 10.1016/s0190-9622(81)70037-9.

Abstract

Carcinoembryonic antigen is detectable by standard unlabeled peroxidase-antiperoxidase technics in eccrine and apocrine secretory and ductal cells. Carcinoembryonic antigen is also present in the cuticle which lines the duct. In eccrine sweat, carcinoembryonic antigen activities were at least thirty times that in serum, using a radioimmunoassay. Carcinoembryonic antigen may form part of the Schiff-positive cuticle and function in the normal homeostasis of eccrine and apocrine glands.

摘要

通过标准的未标记过氧化物酶-抗过氧化物酶技术可在小汗腺和大汗腺的分泌细胞及导管细胞中检测到癌胚抗原。癌胚抗原也存在于导管内衬的角质层中。使用放射免疫测定法，在小汗腺汗液中，癌胚抗原活性至少是血清中的30倍。癌胚抗原可能构成席夫阳性角质层的一部分，并在小汗腺和大汗腺的正常体内平衡中发挥作用。