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[利用放射免疫学研究序列阐明血管加压因子在高血压发病机制中的作用]

[Use of a radioimmunological study sequence for elucidating the role of vasopressor factors in the pathogenesis of hypertension].

作者信息

Gerasimov G M, Martyniuk A D

出版信息

Kardiologiia. 1981 Mar;21(3):60-3.

PMID:7014978
Abstract

An increased content of one of the three hormones that were studied (cortisol, aldosterone and renin) or of their various combinations was found in 58 of 97 patients with hypertensive disease. It is concluded that cortisol plays a predominant role in the mechanism of the maintenance of the blood pressure level in the initial stage of the disease and in a milder course of hypertension. In later periods and in cases with higher blood pressure values, its level is sustained by the renin--angiotensin--aldosterone system. The content of the studied hormones was lower in the remaining 39 patients than in the control group.

摘要

在97例高血压病患者中,有58例被发现所研究的三种激素(皮质醇、醛固酮和肾素)之一或其各种组合的含量增加。得出的结论是,在疾病初期和较轻的高血压病程中,皮质醇在维持血压水平的机制中起主要作用。在后期以及血压值较高的情况下,其水平由肾素 - 血管紧张素 - 醛固酮系统维持。其余39例患者所研究激素的含量低于对照组。

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