Molteni A, Warpeha R L, Brizio-Molteni L, Albertson D F, Kaurs R
Ann Clin Lab Sci. 1979 Nov-Dec;9(6):518-23.
Circadian rhythm of serum aldosterone and cortisol concentrations and of plasma renin activity (PRA) were measured by radioimmunoassay in 10 adults with thermal injuries. The determinations were begun 6 to 48 hours after the injury and continued for five consecutive days four times a day. In all patients, the normal pattern of the circadian rhythm for all three hormones disappeared and values remained quite high at any time of the day or the night. Four patients developed an hypertensive crisis with quite elevated levels of aldosterone, cortisol and plasma renin activity. The same hormones were also found very elevated in two hypotensive patients with 80 percent or more of injured body surface who were in agonal conditions and succumbed to the injury.
采用放射免疫分析法对10名热损伤成人患者的血清醛固酮、皮质醇浓度及血浆肾素活性（PRA）的昼夜节律进行了测定。测定在受伤后6至48小时开始，连续5天，每天4次。所有患者中，这三种激素的昼夜节律正常模式均消失，昼夜任何时候的值都相当高。4名患者发生高血压危象，醛固酮、皮质醇和血浆肾素活性水平显著升高。在两名体表烧伤面积达80%或更多且处于濒死状态并最终死于损伤的低血压患者中，也发现同样这些激素水平非常高。
