产肠毒素大肠杆菌K88介导黏附的遗传分析
Genetic analysis of K88-mediated adhesion of enterotoxigenic Escherichia coli.
作者信息
Kehoe M, Sellwood R, Shipley P, Dougan G
出版信息
Nature. 1981 May 14;291(5811):122-6. doi: 10.1038/291122a0.
DOI:10.1038/291122a0
PMID:7015144
Abstract
Four cistrons (adh) involved in the expression of the K88 adhesion system have been identified and mapped. Three of these (adh A, adh B and adh C) are located in a single operon (I) whereas the fourth (adh D) is expressed from a separate promoter (operon II). The polypeptides encoded by these cistrons have been identified and their role in the formation and regulation of K88 fimbriae (pili) is discussed.
摘要
已鉴定并定位了参与K88黏附系统表达的四个顺反子（adh）。其中三个（adh A、adh B和adh C）位于单个操纵子（I）中，而第四个（adh D）由一个单独的启动子（操纵子II）表达。已鉴定出这些顺反子编码的多肽，并讨论了它们在K88菌毛形成和调控中的作用。
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