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碳酸锂治疗实体瘤患者药物性白细胞减少症

Lithium carbonate in the treatment of drug-induced leukopenia in patients with solid tumors.

作者信息

Scanni A, Tomirotti M, Berra S, Licciardello L, Felicetta I, Bertolini G, Bregni M

出版信息

Tumori. 1980 Dec 31;66(6):729-37. doi: 10.1177/030089168006600607.

DOI:10.1177/030089168006600607
PMID:7015644
Abstract

The authors report on the first part of an ongoing controlled trial (52 cases) on the evaluation of the effectiveness of Li2CO3 treatment of drug-induced leukopenia in patients with solid tumors. The results indicate that treatment with 750 mg/day per os of Li2CO3 for 7 days is capable of raising the leukocyte count to a highly significant extent, without serious side effects. The leukocytosis is due to an increase in neutrophil granulocytes.

摘要

作者报告了一项正在进行的对照试验(52例)的第一部分,该试验旨在评估碳酸锂治疗实体瘤患者药物性白细胞减少症的有效性。结果表明,每天口服750毫克碳酸锂,持续7天,能够在很大程度上显著提高白细胞计数,且无严重副作用。白细胞增多是由于中性粒细胞增加所致。

相似文献

1
Lithium carbonate in the treatment of drug-induced leukopenia in patients with solid tumors.碳酸锂治疗实体瘤患者药物性白细胞减少症
Tumori. 1980 Dec 31;66(6):729-37. doi: 10.1177/030089168006600607.
2
Treatment of neuroleptic-induced leukopenia with lithium carbonate.
Can J Psychiatry. 1981 Nov;26(7):487-9. doi: 10.1177/070674378102600710.
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[Leukocyte count and granulocyte function of children under lithium carbonate therapy treated with cytostatic drugs. A pilot study].
Monatsschr Kinderheilkd. 1984 Jan;132(1):38-42.
4
[Dose-effect relation in therapy of cytostatic-induced leukopenia with lithium carbonate].
Klin Padiatr. 1985 May-Jun;197(3):253-7. doi: 10.1055/s-2008-1033978.
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The effect of lithium carbonate on leukopenia after chemotherapy.碳酸锂对化疗后白细胞减少症的影响。
J Pediatr. 1980 May;96(5):923-7. doi: 10.1016/s0022-3476(80)80583-x.
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The use of lithium carbonate to reduce infection and leukopenia during systemic chemotherapy.使用碳酸锂以减少全身化疗期间的感染和白细胞减少。
N Engl J Med. 1980 Jan 31;302(5):257-60. doi: 10.1056/NEJM198001313020503.
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[Effect of LI2CO3 on leukopenia in children during the treatment of acute leukemia (author's transl)].碳酸锂对儿童急性白血病治疗期间白细胞减少症的影响(作者译)
Lijec Vjesn. 1977 Mar;99(3):163-6.
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The use of lithium carbonate to correct leukopenia during cancer treatment.在癌症治疗期间使用碳酸锂纠正白细胞减少症。
Zhonghua Yi Xue Za Zhi (Taipei). 1989 Mar;43(3):165-70.
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Effects of lithium on thrombopoiesis in patients with low platelet cell counts following chemotherapy or radiotherapy.锂对化疗或放疗后血小板计数低的患者血小板生成的影响。
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[The effect of lithium carbonate against leukopenia during systemic chemotherapy in patients with small cell carcinoma of the lung].[碳酸锂对小细胞肺癌患者全身化疗期间白细胞减少的影响]
Gan To Kagaku Ryoho. 1985 Dec;12(12):2338-44.

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Effect of lithium on chemotherapy-induced neutropenia in Egyptian breast cancer patients; a prospective clinical study.锂对埃及乳腺癌患者化疗引起的中性粒细胞减少症的影响:一项前瞻性临床研究。
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