碳酸锂治疗实体瘤患者药物性白细胞减少症
Lithium carbonate in the treatment of drug-induced leukopenia in patients with solid tumors.
作者信息
Scanni A, Tomirotti M, Berra S, Licciardello L, Felicetta I, Bertolini G, Bregni M
出版信息
Tumori. 1980 Dec 31;66(6):729-37. doi: 10.1177/030089168006600607.
PMID:7015644
Abstract
The authors report on the first part of an ongoing controlled trial (52 cases) on the evaluation of the effectiveness of Li2CO3 treatment of drug-induced leukopenia in patients with solid tumors. The results indicate that treatment with 750 mg/day per os of Li2CO3 for 7 days is capable of raising the leukocyte count to a highly significant extent, without serious side effects. The leukocytosis is due to an increase in neutrophil granulocytes.
摘要
作者报告了一项正在进行的对照试验（52例）的第一部分，该试验旨在评估碳酸锂治疗实体瘤患者药物性白细胞减少症的有效性。结果表明，每天口服750毫克碳酸锂，持续7天，能够在很大程度上显著提高白细胞计数，且无严重副作用。白细胞增多是由于中性粒细胞增加所致。
Zotero 插件