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肠道微循环与跨黏膜液体转运

Intestinal microcirculation and transmucosal fluid transport.

作者信息

Granger D N

出版信息

Am J Physiol. 1981 May;240(5):G343-9. doi: 10.1152/ajpgi.1981.240.5.G343.

DOI:10.1152/ajpgi.1981.240.5.G343
PMID:7015880
Abstract

Blood and lymph capillaries play an important role in removing absorbed fluid from the interstitium of the intestinal mucosa. Data from the literature indicate that hydrostatic and oncotic pressures within the mucosal interstitium primarily determine the partition of absorbed fluid between blood and lymph. Alterations in the density of perfused capillaries and/or capillary permeability during absorption also influence the effectiveness of blood capillaries in removing absorbed fluid. An hypothesis regarding the roles of the interstitium, lymphatics, and capillaries during fluid transport is presented that is based mostly on whole organ studies. The effects of interstitial fluid compartmentation on interpretations of whole organ data are also discussed.

摘要

血液和淋巴毛细血管在从肠黏膜间质中清除吸收的液体方面发挥着重要作用。文献数据表明,黏膜间质内的流体静压和胶体渗透压主要决定了吸收的液体在血液和淋巴之间的分配。吸收过程中灌注毛细血管密度和/或毛细血管通透性的改变也会影响毛细血管清除吸收液体的效率。本文提出了一个关于间质、淋巴管和毛细血管在液体运输过程中作用的假说,该假说主要基于对整个器官的研究。同时还讨论了间质液分隔对整个器官数据解读的影响。

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1
Intestinal microcirculation and transmucosal fluid transport.肠道微循环与跨黏膜液体转运
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