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黄曲霉毒素与疾病

Aflatoxins and disease.

作者信息

Patten R C

出版信息

Am J Trop Med Hyg. 1981 Mar;30(2):422-5. doi: 10.4269/ajtmh.1981.30.422.

Abstract

These days it is widely believed by experts that most cancers are caused by environment factors. The epidemiology of most of these suspected factors is still equivocal. One such factor which has been widely studied is aflatoxin, a chemical produced by the fungus Aspergillus flavus. Because of the widespread distribution of this agent, its known toxicity, and its frequent ingestion by humans, aflatoxin may well be a significant cause of cancer worldwide. This paper attempts to summarize some of the historical and epidemiological evidence regarding aflatoxins and disease.

摘要

如今,专家们普遍认为大多数癌症是由环境因素引起的。其中大多数可疑因素的流行病学仍不明确。黄曲霉毒素就是一个被广泛研究的因素,它是由黄曲霉菌产生的一种化学物质。由于这种物质分布广泛、已知具有毒性且人类经常摄入,黄曲霉毒素很可能是全球癌症的一个重要病因。本文试图总结一些关于黄曲霉毒素与疾病的历史和流行病学证据。

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