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[沙门氏菌病婴儿中条件致病性肠道杆菌的抗生素抗性共轭质粒]

[Conjugated plasmids of antibiotic resistance in conditionally pathogenic enterobacteria in infants with salmonellosis].

作者信息

Gridnev V A, Livkina E G, Grinberg I I, Gridneva L G

出版信息

Antibiotiki. 1981 Apr;26(4):275-9.

PMID:7016023
Abstract

Sensitivity to 10 antibiotics of 1074 strains of opportunistic enterobacteria isolated from 117 children at the age of 2 years was studied (57 healthy children and 60 children with salmonellosis). The structure of the conjugative drug resistance of the opportunistic enterobacteria, the frequency of their isolation and the spectrum correlating with multiple resistance of the strains to 4-10 antibiotics were shown. The frequency of the conjugative determinants of the antibiotics resistance in the opportunistic bacteria isolated from the patients with salmonellosis was higher. The structure of the conjugative drug resistance of the opportunistic enterobacteria in the dynamics of the salmonellosis process was close to the transmissive R-plasmid resistance of S. typhimurium.

摘要

对从117名2岁儿童(57名健康儿童和60名沙门氏菌病患儿)中分离出的1074株机会性肠道杆菌进行了对10种抗生素的敏感性研究。展示了机会性肠道杆菌的接合耐药性结构、它们的分离频率以及与菌株对4 - 10种抗生素多重耐药相关的谱。从沙门氏菌病患者中分离出的机会性细菌中抗生素耐药性的接合决定因素频率更高。在沙门氏菌病过程动态中,机会性肠道杆菌的接合耐药性结构与鼠伤寒沙门氏菌的可传递R质粒耐药性相近。

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