[Plasmid resistance of the enterobacteria isolated in intestinal disorders in children].

Resistance to antibiotics and sulfanilamides was determined in enterobacteria (E. coli, Pr. mirabilis, Sh. sonnei, Sh. flexneri) isolated from children with intestinal disorders. Elimination of the resistance determinants in polyresistant strains, conjugation of R plasmids (75 per cent in Pr. mirabilis, 70 per cent in E. coli, 78 per cent in Sh. sonnei, 69 per cent in Sh. flexneri), mobilization of nonconjugative plasmids on triple crossing and capacity of R plasmids for repression of the F-factor functions were studied. The data of the study are evident of the plasmid background in enterobacteria isolated from children with intestinal disorders and confirm the plasmid nature of the resistance in the predominating number of the strains. It is suggested that Proteus plays a significant role in the prevalence of plasmid resistance among enterobacteria.