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用单克隆抗体鉴定的大鼠淋巴细胞群体在大鼠淋巴组织中的定位。

The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues.

作者信息

Barclay A N

出版信息

Immunology. 1981 Apr;42(4):593-600.

PMID:7016746
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1458260/
Abstract

The localisation of subpopulations of T lymphocytes as defined by the monoclonal antibodies W3/25 and MRC OX 8 was determined by an indirect immunoperoxidase technique on cryostat sections of rat lymphoid tissues. Both subpopulations were present throughout T-dependent areas with only scattered T cells, largely W3/25 positive, in the B areas. The W3/25 antigen was also found on macrophages in the medulla of lymph nodes and in the peritoneal cavity and liver.

摘要

采用间接免疫过氧化物酶技术，在大鼠淋巴组织的低温切片上，确定了由单克隆抗体W3/25和MRC OX 8所界定的T淋巴细胞亚群的定位。在整个T细胞依赖区均存在这两个亚群，而在B细胞区仅有散在的T细胞，其中大部分为W3/25阳性。在淋巴结髓质、腹腔和肝脏的巨噬细胞上也发现了W3/25抗原。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1623/1458260/9f9e6b6d20da/immunology00245-0097-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1623/1458260/8c430f481a10/immunology00245-0096-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1623/1458260/9f9e6b6d20da/immunology00245-0097-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1623/1458260/8c430f481a10/immunology00245-0096-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1623/1458260/9f9e6b6d20da/immunology00245-0097-a.jpg

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