Fraser R, Brown J J, Lever A F, Morton J J, Robertson J I
Int J Obes. 1981;5 suppl 1:115-23.
The biochemistry of the renin-angiotensin system has been outlined. The relationship between plasma angiotension II levels, basal or raised as a result of infusion, and blood pressure and aldosterone has been explored in normal human subjects and animals, showing how these relationships can be modified by changes in sodium status and duration of exposure to high circulating levels of the octapeptide. Finally, the relationship has been examined in different categories of hypertensive disease, such as essential hypertension.
肾素-血管紧张素系统的生物化学已被概述。在正常人类受试者和动物中，研究了血浆血管紧张素II水平（基础水平或因输注而升高）与血压和醛固酮之间的关系，显示了这些关系如何因钠状态的变化以及暴露于高循环水平八肽的持续时间而改变。最后，在不同类型的高血压疾病（如原发性高血压）中研究了这种关系。
