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[Changes in the radiosensitivity of Escherichia coli cells with cholesterol incorporated into their membranes].[胆固醇掺入细胞膜后大肠杆菌细胞放射敏感性的变化]
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本文引用的文献

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Mutations of Bacteria from Virus Sensitivity to Virus Resistance.细菌从对病毒敏感到对病毒抗性的突变。
Genetics. 1943 Nov;28(6):491-511. doi: 10.1093/genetics/28.6.491.
2
Fatty Acid Composition of Escherichia coli as a Possible Controlling Factor of the Minimal Growth Temperature.大肠杆菌的脂肪酸组成作为最低生长温度的一个可能控制因素
J Bacteriol. 1965 Jul;90(1):141-6. doi: 10.1128/jb.90.1.141-146.1965.
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EFFECT OF TEMPERATURE ON THE COMPOSITION OF FATTY ACIDS IN ESCHERICHIA COLI.温度对大肠杆菌脂肪酸组成的影响
J Bacteriol. 1962 Dec;84(6):1260-7. doi: 10.1128/jb.84.6.1260-1267.1962.
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Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
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CHOLESTEROL AND CHOLESTEROL ESTERS IN MYCOPLASMA.支原体中的胆固醇和胆固醇酯
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Sterols in membranes: growth characteristics and membrane properties of Mycoplasma capricolum cultured on cholesterol and lanosterol.膜中的甾醇：在胆固醇和羊毛甾醇上培养的山羊支原体的生长特性和膜特性
Biochemistry. 1980 Apr 1;19(7):1467-72. doi: 10.1021/bi00548a032.
7
Differential effects of ethanol and hexanol on the Escherichia coli cell envelope.乙醇和己醇对大肠杆菌细胞膜的不同作用
J Bacteriol. 1980 Nov;144(2):481-8. doi: 10.1128/jb.144.2.481-488.1980.
8
Alcohol-induced changes in the phospholipid molecular species of Escherichia coli.酒精引起的大肠杆菌磷脂分子种类的变化。
J Bacteriol. 1980 Jun;142(3):1040-4. doi: 10.1128/jb.142.3.1040-1044.1980.
9
Influence of lipid components of Mycoplasma laidlawii membranes on osmotic fragility of cells.莱氏无胆甾原体细胞膜脂质成分对细胞渗透脆性的影响。
J Bacteriol. 1966 Feb;91(2):609-16. doi: 10.1128/jb.91.2.609-616.1966.
10
Synthesis of macromolecules by Escherichia coli near the minimal temperature for growth.大肠杆菌在接近生长最低温度时对大分子的合成。
J Bacteriol. 1967 Jul;94(1):157-64. doi: 10.1128/jb.94.1.157-164.1967.

大肠杆菌未能响应胆固醇诱导的膜流动性变化而改变其脂肪酸组成。

Failure of Escherichia coli to alter its fatty acid composition in response to cholesterol-induced changes in membrane fluidity.

作者信息

Eaton L C, Erdos G W, Vreeland N L, Ingram L O

出版信息

J Bacteriol. 1981 Jun;146(3):1151-3. doi: 10.1128/jb.146.3.1151-1153.1981.

DOI:10.1128/jb.146.3.1151-1153.1981
PMID:7016828
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC216971/
Abstract

Substantial amounts of exogenously supplied cholesterol were incorporated into the membranes of Escherichia coli during growth and caused a large decrease in membrane fluidity. Although no compensatory changes in fatty acid composition were observed, the incorporation of cholesterol did not affect the rate of growth of E. coli or interfere with the changes in fatty acid composition which normally occur during growth at different temperatures.

摘要

在生长过程中，大量外源供应的胆固醇被整合到大肠杆菌的膜中，导致膜流动性大幅降低。虽然未观察到脂肪酸组成的补偿性变化，但胆固醇的整合并未影响大肠杆菌的生长速率，也未干扰在不同温度下生长时正常发生的脂肪酸组成变化。