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大肠杆菌未能响应胆固醇诱导的膜流动性变化而改变其脂肪酸组成。

Failure of Escherichia coli to alter its fatty acid composition in response to cholesterol-induced changes in membrane fluidity.

作者信息

Eaton L C, Erdos G W, Vreeland N L, Ingram L O

出版信息

J Bacteriol. 1981 Jun;146(3):1151-3. doi: 10.1128/jb.146.3.1151-1153.1981.

Abstract

Substantial amounts of exogenously supplied cholesterol were incorporated into the membranes of Escherichia coli during growth and caused a large decrease in membrane fluidity. Although no compensatory changes in fatty acid composition were observed, the incorporation of cholesterol did not affect the rate of growth of E. coli or interfere with the changes in fatty acid composition which normally occur during growth at different temperatures.

摘要

在生长过程中,大量外源供应的胆固醇被整合到大肠杆菌的膜中,导致膜流动性大幅降低。虽然未观察到脂肪酸组成的补偿性变化,但胆固醇的整合并未影响大肠杆菌的生长速率,也未干扰在不同温度下生长时正常发生的脂肪酸组成变化。

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本文引用的文献

5
CHOLESTEROL AND CHOLESTEROL ESTERS IN MYCOPLASMA.支原体中的胆固醇和胆固醇酯
J Gen Microbiol. 1965 Jan;38:153-60. doi: 10.1099/00221287-38-1-153.

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