Eaton L C, Erdos G W, Vreeland N L, Ingram L O
J Bacteriol. 1981 Jun;146(3):1151-3. doi: 10.1128/jb.146.3.1151-1153.1981.
Substantial amounts of exogenously supplied cholesterol were incorporated into the membranes of Escherichia coli during growth and caused a large decrease in membrane fluidity. Although no compensatory changes in fatty acid composition were observed, the incorporation of cholesterol did not affect the rate of growth of E. coli or interfere with the changes in fatty acid composition which normally occur during growth at different temperatures.
在生长过程中,大量外源供应的胆固醇被整合到大肠杆菌的膜中,导致膜流动性大幅降低。虽然未观察到脂肪酸组成的补偿性变化,但胆固醇的整合并未影响大肠杆菌的生长速率,也未干扰在不同温度下生长时正常发生的脂肪酸组成变化。