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酒精引起的大肠杆菌磷脂分子种类的变化。

Alcohol-induced changes in the phospholipid molecular species of Escherichia coli.

作者信息

Berger B, Carty C E, Ingram L O

出版信息

J Bacteriol. 1980 Jun;142(3):1040-4. doi: 10.1128/jb.142.3.1040-1044.1980.

Abstract

In Escherichia coli, the additon of ethanol resulted in the synthesis of an increased proportion of phospholipids containing two unsaturated fatty acids. The addition of hexanol resulted in the opposite effect, an increase in the proportion of monounsaturated molecular species. The alcohol-induced changes were quantitatively similar to those caused by changing growth temperature. These results suggest that both adaptation to temperature and alcohol-induced changes in lipid composition share some common regulatory features.

摘要

在大肠杆菌中,添加乙醇导致含有两个不饱和脂肪酸的磷脂合成比例增加。添加己醇则产生相反的效果,即单不饱和分子种类的比例增加。酒精诱导的变化在数量上与改变生长温度引起的变化相似。这些结果表明,对温度的适应和酒精诱导的脂质组成变化具有一些共同的调节特征。

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本文引用的文献

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The effects of long-chain alcohols on membrane lipids and the (Na++K+)-ATPase.
Biochim Biophys Acta. 1973 Jul 6;311(3):417-22. doi: 10.1016/0005-2736(73)90322-2.
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The effects of alcohols on lipid bilayers: a spin label study.
Biochim Biophys Acta. 1972 Jun 20;266(3):597-602. doi: 10.1016/0006-3002(72)90003-0.
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Interactions between anesthetics and lipid mixtures. Normal alcohols.
Biochemistry. 1976 Jun 1;15(11):2448-54. doi: 10.1021/bi00656a031.

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