卡托普利用于慢性肾衰竭和肾移植患者的顽固性高血压
Captopril for refractory hypertension in patients with chronic renal failure and renal transplantation.
作者信息
Hamilton D V, Evans D B, Maidment G, Pryor J S
出版信息
J R Soc Med. 1981 May;74(5):357-62.
Abstract
The converting-enzyme inhibitor, captopril, was given to ten patients with refractory severe hypertension of renal origin: 6 patients had chronic renal failure, 3 patients had hypertension following renal transplantation, and one patient had hypertension and congestive cardiac failure. Control of blood pressure was achieved with doses from 78 to 400 mg/day. Severe hyperkalaemia occurred in one patients, ageusia (dose dependent) in another, and one patients withdrew from treatment because of nausea.
摘要
给10例顽固性肾源性重度高血压患者服用转换酶抑制剂卡托普利：6例患有慢性肾衰竭，3例在肾移植后出现高血压，1例患有高血压和充血性心力衰竭。通过每日78至400毫克的剂量实现了血压控制。1例患者出现严重高钾血症，另1例出现味觉丧失（剂量依赖性），1例患者因恶心退出治疗。
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本文引用的文献
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3
Captopril and frusemide in severe drug-resistant hypertension.卡托普利和呋塞米用于重度耐药性高血压
Lancet. 1980 Jul 19;2(8186):108-10. doi: 10.1016/s0140-6736(80)90002-1.
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Combined treatment of severe intractable hypertension with captopril and diuretic.卡托普利与利尿剂联合治疗重度顽固性高血压
Lancet. 1980 Jul 19;2(8186):105-8. doi: 10.1016/s0140-6736(80)90001-x.
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Evaluation of a new antihypertensive agent. Minoxidil.一种新型抗高血压药物——米诺地尔的评估。
JAMA. 1980 Jul 4;244(1):73-5.
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Captopril associated granulocytopenia in hypertension after renal transplantation.肾移植后高血压患者中卡托普利相关的粒细胞减少症
Lancet. 1980 Apr 26;1(8174):927-8. doi: 10.1016/s0140-6736(80)90854-5.
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Captopril: reversible renal failure with severe hyperkalaemia.卡托普利：可导致伴有严重高钾血症的可逆性肾衰竭。
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8
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