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尼日利亚儿童寄生虫感染抗体的流行情况。

Prevalence of antibodies to parasitic infections in Nigerian children.

作者信息

Thomas V, Fabiyi A, Adeniyi A

出版信息

J Trop Med Hyg. 1981 Jun;84(3):113-6.

PMID:7017156
Abstract

Sixty-six sera from Nigerian children who attended a paediatric clinic at University College Hospital, Ibadan were tested with Plasmodium falciparum, P. brazilianum, Entamoeba histolytica, Toxoplasma gondii and Schistosoma mansoni antigens using indirect fluorescent antibody technique. These sera were tested using ELISA technique for Schistosoma antibodies. Sera from all proven cases of infections gave positive results. Highest antibody prevalence rate was for P. falciparum (69.6%), followed by P. malariae (63.6%) and E. histolytica (42.4%) infections. About 17% and 16% were reactive with Toxoplasma and Schistosoma antigens respectively. Only nine (13.6%) children were negative with all antigens. Forty-four (66.6%) children were positive to two or more parasitic antibodies indicating exposure to those diseases. The significance of these antibodies in children is discussed.

摘要

使用间接荧光抗体技术,对来自伊巴丹大学学院医院儿科诊所的66名尼日利亚儿童的血清进行了检测,检测对象包括恶性疟原虫、巴西疟原虫、溶组织内阿米巴、弓形虫和曼氏血吸虫抗原。使用酶联免疫吸附测定(ELISA)技术对这些血清进行血吸虫抗体检测。所有经证实的感染病例的血清检测结果均为阳性。抗体流行率最高的是恶性疟原虫(69.6%),其次是三日疟原虫(63.6%)和溶组织内阿米巴(42.4%)感染。分别约有17%和16%的血清与弓形虫和血吸虫抗原呈反应性。只有9名(13.6%)儿童的所有抗原检测均为阴性。44名(66.6%)儿童对两种或更多种寄生虫抗体呈阳性,表明他们接触过这些疾病。本文讨论了这些抗体在儿童中的意义。

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引用本文的文献

1
Human Toxoplasma gondii infection in Nigeria: a systematic review and meta-analysis of data published between 1960 and 2019.尼日利亚人体弓形虫感染:1960 年至 2019 年发表数据的系统评价和荟萃分析。
BMC Public Health. 2020 Jun 6;20(1):877. doi: 10.1186/s12889-020-09015-7.