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[瓜西柳酯:一种具有香脂-抗炎作用的新分子。临床研究]

[Guacetisal: a new molecule with balsamic-antiphlogistic action. Clinical study].

作者信息

Marchesani F, Rizzo S, Salvini P

出版信息

Minerva Med. 1981 Feb 28;72(7):401-8.

PMID:7017491
Abstract

An open clinical trial was run on the therapeutic efficacy of a new balsamic-antiinflammatory molecule, guacetisal (presented as 500 mg Broncaspin capsules). The drug was given for a minimum of 7 days to 45 male and female patients with an average age of 64 yr suffering from variously serious diseases of the airways. The concomitant administration of fluidifying, balsamic, steroid, antipyretic and anti-inflammatory drugs was avoided, whereas various combinations of cardiokinetics, diuretics, theophyllines, and antibiotics were used where required. Clinical assessment of the parameters chosen pointed to the good therapeutic activity of the preparation, which is specifically indicated in inflammatory conditions of the airways, especially chronic forms subject to periodic recrudescence. Its equally good tolerability serves to make guacetisal extremely easy to use, with the results that its employment in non-specialist environments can also be recommended.

摘要

对一种新型香脂抗炎分子瓜西他柳(以500毫克的Broncaspin胶囊形式呈现)的治疗效果进行了一项开放性临床试验。该药物给予了45名平均年龄为64岁、患有各种严重气道疾病的男性和女性患者,疗程至少7天。避免同时使用化痰、香脂、类固醇、退烧药和消炎药,而在需要时使用了各种强心剂、利尿剂、茶碱和抗生素的组合。对所选参数的临床评估表明该制剂具有良好的治疗活性,特别适用于气道的炎症状况,尤其是易周期性复发的慢性形式。其同样良好的耐受性使得瓜西他柳极易使用,因此也可推荐在非专业环境中使用。

相似文献

1
[Guacetisal: a new molecule with balsamic-antiphlogistic action. Clinical study].[瓜西柳酯:一种具有香脂-抗炎作用的新分子。临床研究]
Minerva Med. 1981 Feb 28;72(7):401-8.
2
[Clinical evaluation of the therapeutic effectiveness of a new drug with anti-inflammatory-balsamic action, guacetisal, in respiratory tract diseases].[新型具有抗炎香脂作用的药物瓜西他酯治疗呼吸道疾病的疗效临床评估]
Minerva Med. 1981 Feb 28;72(7):325-32.
3
[Broncaspin in respiratory diseases in pediatrics. Clinical contribution].[溴己新在儿科呼吸道疾病中的应用。临床贡献]
Minerva Med. 1981 Feb 28;72(7):417-22.
4
[The use of a new balsamic expectorant in bronchopulmonary pathology in children].[一种新型香脂性祛痰剂在儿童支气管肺疾病中的应用]
Minerva Med. 1981 Feb 28;72(7):363-6.
5
[Clinical trials of a new preparation in chronic bronchopneumopathies].[一种新制剂用于慢性支气管肺炎的临床试验]
Minerva Med. 1981 Feb 28;72(7):451-8.
6
[Guacetisal in the treatment of acute and chronic bronchopneumopathy].[瓜西沙星治疗急慢性支气管肺炎]
Minerva Med. 1981 Feb 28;72(7):347-53.
7
[Clinical evaluation of the activity of 2 preparations with similar action in bronchopneumopathies in the aged].[两种作用相似的制剂在老年支气管肺炎中的活性临床评估]
Minerva Med. 1981 Feb 28;72(7):393-400.
8
[Broncaspin in the therapy of pediatric diseases of the respiratory tract].
Minerva Med. 1981 Feb 28;72(7):435-42.
9
[Clinical trial of guacetisal in aged subjects with inflammatory diseases of the respiratory tract].[瓜西沙星用于老年呼吸道炎症性疾病患者的临床试验]
Clin Ter. 1982 Dec 15;103(5):527-33.
10
[The use of guacetisal in bronchopulmonary pathology in children].[瓜西他酯在儿童支气管肺病理学中的应用]
Minerva Pediatr. 1983 Feb;35(3):129-33.