Mora P, Levi P, Marostica G
Minerva Med. 1981 Feb 28;72(7):417-22.
Broncaspin (guacetisal) has been administered rectally to 42 children suffering from inflammatory diseases of the upper and lower airways, most cases being complicated by bronchospasm. Treatment involving a dose of 1-2 suppositories of 0.5 g/die up to six years of age, and 2 suppositories/die after the sixth year always produced a good antipyretic and anti-cough effect. The preparation was outstanding for speed of action, local and general tolerance, and the absence of haematological, hepatic or renal side-effects. The new drug is considered to be a valuable instrument for anti-inflammatory and anti-cough treatment in acute diseases of the airways in infancy.
已对42名患有上、下呼吸道炎症性疾病的儿童直肠给药布罗卡斯平（胍乙柳酯），大多数病例伴有支气管痉挛。治疗时，6岁及以下儿童每日剂量为1 - 2枚0.5克的栓剂，6岁以上儿童每日2枚栓剂，总能产生良好的退热和止咳效果。该制剂在起效速度、局部和全身耐受性以及无血液学、肝脏或肾脏副作用方面表现出色。这种新药被认为是治疗婴儿期气道急性疾病抗炎和止咳的有效药物。
