Allen J B, Weiner L B
Pediatrics. 1981 Feb;67(2):292-5.
Forty episodes of sepsis in 28 patients with leukemia or lymphoma were reviewed. Streptococcus pneumoniae accounted for 14 episodes and was the most frequent etiologic agent isolated. Escherichia coli and Staphylococcus aureus accounted for an additional 16 episodes. No patients with pneumococcal sepsis died whereas the overall mortality was 25%. Five of the patients with pneumococcal sepsis had polymorphonuclear leukocyte counts less than 500/cu mm. All patients in remission who had pneumococcal sepsis had a leukocytosis in response to their infection. Foci in patients with pneumococcal sepsis were identified in 50% of the episodes and all were confined to the respiratory tract.
回顾了28例白血病或淋巴瘤患者的40次脓毒症发作。肺炎链球菌导致了14次发作，是分离出的最常见病原体。大肠杆菌和金黄色葡萄球菌又导致了16次发作。肺炎球菌性脓毒症患者无一死亡，而总体死亡率为25%。5例肺炎球菌性脓毒症患者的多形核白细胞计数低于500/立方毫米。所有处于缓解期且患肺炎球菌性脓毒症的患者在感染后均出现白细胞增多。50%的肺炎球菌性脓毒症发作患者中发现了病灶，且所有病灶均局限于呼吸道。
