Kokot F, Paliwoda T, Bułanowski Z, Bochenek A, Herman Z, Wieczorek M, Dobosz J
Proc Eur Dial Transplant Assoc. 1980;17:589-97.
In seven splenectomised dogs a left renal vein-splenic vein anastomosis was performed and the right kidney removed. Eighteen to twenty-four months after portalisation of renal venous blood no significant alterations of liver function tests were found. Long-term diversion of renal venous blood into the liver was followed by a slight increase of creatinine and 25(OH)D3, a decrease of alpha-amino acid nitrogen in blood plasma and of plasma renin activity in peripheral blood, by symptoms of slight carbohydrate intolerance despite hyperinsulinaemia and a slight decrease of erythrocytosis. No influence of this procedure on plasma proteins, lipids, electrolytes, aldosterone and cortisol was observed. No morphological abnormalities in liver and kidney tissues were found.
在7只脾切除的狗身上进行了左肾静脉-脾静脉吻合术，并切除了右肾。肾静脉血门脉化18至24个月后，未发现肝功能检查有明显改变。肾静脉血长期分流至肝脏后，肌酐和25(OH)D3略有升高，血浆中α-氨基酸氮和外周血中血浆肾素活性降低，尽管存在高胰岛素血症，但仍有轻微的碳水化合物不耐受症状，红细胞增多症略有减轻。未观察到该手术对血浆蛋白、脂质、电解质、醛固酮和皮质醇有影响。在肝脏和肾脏组织中未发现形态学异常。
