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长期将肾静脉血分流至门静脉系统的代谢效应。

Metabolic effects of long-term diversion of renal venous blood into the portal system.

作者信息

Kokot F, Paliwoda T, Bułanowski Z, Bochenek A, Herman Z S, Wieczorek M, Dobosz J

出版信息

Acta Physiol Pol. 1983 Jul-Aug;34(4):467-75.

PMID:6375261
Abstract

In 7 splenectomized dogs a left renal vein-splenic vein anastomosis was performed and the right kidney removed. Eighteen to twenty-four months after portalization of renal venous blood no significant alterations of liver function tests were observed. Long-term diversion of renal venous blood into the liver was followed by a slight increase of creatinine and 25-OH-D, a decrease of alpha-amino acid nitrogen in blood plasma and of plasma renin activity in peripheral blood, by signs of slight carbohydrate intolerance despite hyperinsulinaemia, and a slight decrease of erythrocyte count. No influence of this procedure on plasma proteins, lipids, electrolytes, aldosterone and cortisol was found. No morphological abnormalities in the liver and kidney tissue were found.

摘要

在7只脾切除的狗身上进行了左肾静脉-脾静脉吻合术,并切除了右肾。肾静脉血门脉化18至24个月后,未观察到肝功能测试有明显改变。肾静脉血长期分流至肝脏后,肌酐和25-羟基维生素D略有升高,血浆中α-氨基酸氮和外周血中血浆肾素活性降低,尽管存在高胰岛素血症但仍有轻微的碳水化合物不耐受迹象,红细胞计数略有下降。未发现该手术对血浆蛋白、脂质、电解质、醛固酮和皮质醇有影响。在肝脏和肾脏组织中未发现形态学异常。

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Metabolic effects of long-term diversion of renal venous blood into the portal system.长期将肾静脉血分流至门静脉系统的代谢效应。
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