大鼠主动脉中前列环素生成随年龄增长的增加。
Age-related increase in prostacyclin production in the rat aorta.
作者信息
Panganamala R V, Hanumaiah B, Merola A J
出版信息
Prostaglandins Med. 1981 Feb;6(2):233-5. doi: 10.1016/0161-4630(81)90094-x.
PMID:7017783
Abstract
Normal Sprague-Dawley rats convert a substantial percentage of exogenous arachidonic acid to prostacyclin. This conversion can be quantitated by an aqueous sampling technique utilizing thin layer chromatography and liquid scintillation counting. There is a clear age-related increase in this conversion that can be demonstrated in aortas from rats of 3 weeks to 20 weeks of age.
摘要
正常的斯普拉格-道利大鼠可将相当比例的外源性花生四烯酸转化为前列环素。这种转化可以通过利用薄层色谱法和液体闪烁计数的水相采样技术进行定量。在3周龄至20周龄大鼠的主动脉中可以证明，这种转化存在明显的与年龄相关的增加。
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