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用于儿童急性癫痫发作家庭治疗的直肠用安定溶液

Diazepam rectal solution for home treatment of acute seizures in children.

作者信息

Hoppu K, Santavuori P

出版信息

Acta Paediatr Scand. 1981;70(3):369-72. doi: 10.1111/j.1651-2227.1981.tb16565.x.

Abstract

To gain clinical experience of treating acute convulsions in children with diazepam rectal solution, 17 epileptic children with prolonged convulsions were treated at home. The drug was used 65 times. On 2/3 of all occasions the seizure was interrupted in less than 15 min. A starting dose of 0.5 mg/kg is recommended, with a maximum of 20 mg per single dose. One patient had respiratory difficulties, one dizziness and two skin reactions.

摘要

为获取使用地西泮直肠溶液治疗儿童急性惊厥的临床经验,17名惊厥持续时间较长的癫痫患儿在家中接受了治疗。该药物共使用了65次。在所有用药情况的2/3中,惊厥在不到15分钟内得到缓解。建议起始剂量为0.5毫克/千克,单次最大剂量为20毫克。1例患者出现呼吸困难,1例出现头晕,2例出现皮肤反应。

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