Hoppu K, Santavuori P
Acta Paediatr Scand. 1981;70(3):369-72. doi: 10.1111/j.1651-2227.1981.tb16565.x.
To gain clinical experience of treating acute convulsions in children with diazepam rectal solution, 17 epileptic children with prolonged convulsions were treated at home. The drug was used 65 times. On 2/3 of all occasions the seizure was interrupted in less than 15 min. A starting dose of 0.5 mg/kg is recommended, with a maximum of 20 mg per single dose. One patient had respiratory difficulties, one dizziness and two skin reactions.
为获取使用地西泮直肠溶液治疗儿童急性惊厥的临床经验,17名惊厥持续时间较长的癫痫患儿在家中接受了治疗。该药物共使用了65次。在所有用药情况的2/3中,惊厥在不到15分钟内得到缓解。建议起始剂量为0.5毫克/千克,单次最大剂量为20毫克。1例患者出现呼吸困难,1例出现头晕,2例出现皮肤反应。