Focà A
Ann Sclavo. 1980 Jan-Feb;22(1):22-6.
Poliovirus vaccines (Salk-type and Sabin-type) have virtually eliminated paralytic poliomyelitis. Important subjects of study are the back-mutation of the type 3 degrees, the effect of the Sabin vaccine in addition to Salk vaccine, the development of vaccines to virus substructures and the synthetic-vaccines.
脊髓灰质炎疫苗(索尔克型和萨宾型)实际上已消除了麻痹性脊髓灰质炎。重要的研究课题包括3型的回复突变、萨宾疫苗相对于索尔克疫苗的效果、针对病毒亚结构的疫苗开发以及合成疫苗。