A method for the assessment of osteoneogenesis in experimental bone grafts.

There is a simple approach to objective quantification of osteogenesis in experimental head and neck bone grafts. The method is based on direct and precise graft measurements using routine histologic techniques and microphotographs. It has proved valuable in the study of cases in which new bone production occurs in layers, eg, in onlay bone grafts and periosteal osteogenesis. It is not practical when new bone formation is irregular or multicentric. The method is introduced to be used in conjunction with available techniques, eg, tetracycline hydrochloride labeling and roentgenography.