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携带不同“非经典”修饰的噬菌体T3的血清学特征

[Serological characterization of bacteriophage T3 carrying different "non-classical" modifications].

作者信息

Gachechiladze K K, Kriuger D Kh, Balardzhishvili N Sh, Khanzen Z, Rozenta'l Kh A

出版信息

Mol Biol (Mosk). 1981 May-Jun;15(3):583-8.

PMID:7019671
Abstract

The antigenic properties of bacteriophage T3 and a mutant T3/R7 which undergoes "non-classical" modification and restriction are compared. The "non-classical" modification of T3/R7 consists of a host-dependent, reversible change in the adsorption capacity of phage on different host strains. We have shown that this modification is connected with changes in the antigenic properties of phage components involved in phage absorption to the host cell. This means that, in contrast to the "classical" host-control-led modification and restriction of DNA, the "non-classical" modification and restriction of phage is based on protein modification.

摘要

对噬菌体T3和经历“非经典”修饰与限制的突变体T3/R7的抗原特性进行了比较。T3/R7的“非经典”修饰包括噬菌体对不同宿主菌株吸附能力的宿主依赖性可逆变化。我们已经表明,这种修饰与参与噬菌体吸附到宿主细胞的噬菌体成分的抗原特性变化有关。这意味着,与由宿主控制的DNA“经典”修饰和限制不同,噬菌体的“非经典”修饰和限制是基于蛋白质修饰的。

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