Corkey C W, Barker G A, Edmonds J F, Mok P M, Newth C J
Crit Care Med. 1981 Aug;9(8):587-90. doi: 10.1097/00003246-198108000-00007.
The percentage of change in tracheal diameter (TD% change), as assessed by an objective radiological measurement, was used along with a simple subjective clinical score to assess response to therapy in upper airway obstruction in 14 patients with acute infectious croup. Studies were performed on the 14 patients, each of whom was randomly assigned to one of two treatment groups: distilled water or racemic epinephrine (RE), both being nebulized and delivered by manual IPPB. The objective radiological assessment and the subjective clinical score both confirmed that RE is significantly (p less than 0.005) more effective than distilled water in the acute relief of upper airway obstruction. The more precise radiological assessment may be of value in determining objectively better drug therapy for infectious croup.
通过客观放射学测量评估的气管直径变化百分比（TD%变化），与一个简单的主观临床评分一起，用于评估14例急性感染性喉炎患者上气道梗阻的治疗反应。对这14例患者进行了研究，每位患者被随机分配到两个治疗组之一：蒸馏水组或消旋肾上腺素（RE）组，二者均通过手动间歇性正压通气进行雾化给药。客观放射学评估和主观临床评分均证实，在急性缓解上气道梗阻方面，RE显著（p<0.005）比蒸馏水更有效。更精确的放射学评估可能在客观确定感染性喉炎更好的药物治疗方面具有价值。
